Apical periodontitis is one of the most common inflammatory diseases that affect humans and is caused by microbial infection of the dental root canal system. A thorough understanding of the etiology and pathogenesis of apical periodontitis is essential for high-quality endodontic practice based on a solid scientific foundation. The first section of this book deals with microbiologic and pathophysiologic aspects of the different manifestations of apical periodontitis, while the second section describes the best evidence for predictable treatment and prevention of the disease. Clinical techniques and protocols to treat endodontic infections are described in detail.

This new edition boasts a team of renowned authorities in the field that contribute state-of-the-art evidence about the biology and practice of the endodontic treatment of teeth with infected root canals. The content is supplemented with numerous full-color illustrations and radiographs. This book is a definitive guide to those involved with the prevention and treatment of endodontic infections. 717 illustrations. Contributors: Hacer Aksel • Adham A. Azim • Sebastian Bürklein • Gilberto Debelian • Ashraf F. Fouad • Kishor Gulabivala • Michael Hülsmann • Anil Kishen • Hélio P. Lopes • Jenifer Martín-González • Yuan-Ling Ng • Xenos Petridis • Domenico Ricucci • Edgar Schäfer • Juan José Segura-Egea • Luc van der Sluis. Contents: Section 1. The infection 1. Endodontic infections and the etiology of apical periodontitis – an overview 2. The invaders: bacterial biofilm communities and pathogenicity 3. The defense: host-pathogen interactions and immune response