This issue of Clinics in Plastic Surgery, guest edited by Dr. Lee L.Q. Pu, is devoted to. This issue will include an overview of current concepts and techniques of facial fat grafting, discuss personal approaches from the experts in fat grafting for facial rejuvenation, and show techniques for fat grafting for facial rejuvenation with nanofat grafts, cryopreserved fat grafts, and SVF-gel. Articles will further discuss fat grafting for facial contouring of the temporal region and midface, nose and chin, and unilateral face with SVF. Pan-facial fat injection approach to facial contouring in young Asian patients and fat grafting for the treatment of facial burns and burn scars, facial scleroderma, facial scars, and secondary facial deformity will also be discussed.